A Retrospective Comparison of Collagen Nerve Conduits and Processed Nerve Allografts for the Reconstruction of Digital Nerve Gaps
نویسندگان
چکیده
منابع مشابه
Nerve conduits for nerve repair or reconstruction.
Advances in treating peripheral nerve lesions have resulted from research in nerve regeneration and the use biomaterials as well as synthetic materials. When direct tensionless repair of peripheral nerve lesions is not possible, nerve conduits may be used to bridge digital sensory nerve gaps of ≤3 cm. Nerve autograft is the benchmark for larger, longer, mixed, or motor nerve defects. Biologic, ...
متن کاملCollagen Type I Conduits for the Regeneration of Nerve Defects
To date, reliable data to support the general use of biodegradable materials for bridging nerve defects are still scarce. We present the outcome of nerve regeneration following type I collagen conduit nerve repair in patients with large-diameter nerve gaps. Ten patients underwent nerve repair using a type I collagen nerve conduit. Patients were re-examined at a minimal follow-up of 14.0 months ...
متن کاملProcessed nerve allografts for peripheral nerve reconstruction: a multicenter study of utilization and outcomes in sensory, mixed, and motor nerve reconstructions.
PURPOSE As alternatives to autograft become more conventional, clinical outcomes data on their effectiveness in restoring meaningful function is essential. In this study we report on the outcomes from a multicenter study on processed nerve allografts (Avance® Nerve Graft, AxoGen, Inc). PATIENTS AND METHODS Twelve sites with 25 surgeons contributed data from 132 individual nerve injuries. Data...
متن کاملNanofibrous collagen nerve conduits for spinal cord repair.
Nerve regeneration in an injured spinal cord is often restricted, contributing to the devastating outcome of neurologic impairment below the site of injury. Although implantation of tissue-engineered scaffolds has evolved as a potential treatment method, the outcomes remain sub-optimal. One possible reason may be the lack of topographical signals from these constructs to provide contact guidanc...
متن کاملOvercoming short gaps in peripheral nerve repair: conduits and human acellular nerve allograft.
Nerve conduits and acellular nerve allograft offer efficient and convenient tools for overcoming unexpected gaps during nerve repair. Both techniques offer guidance for migrating Schwann cells and axonal regeneration though utilizing very different scaffolds. The substantially greater amount of animal and clinical data published on nerve conduits is marked by wide discrepancies in results that ...
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ژورنال
عنوان ژورنال: The Journal of Hand Surgery
سال: 2018
ISSN: 0363-5023
DOI: 10.1016/j.jhsa.2018.06.040